Florence, county, east-central South Carolina, U.S. The Great Pee Dee River constitutes its eastern boundary, and the Lynches River part of its western. The county is situated in a low-lying, generally flat area of the Coastal Plain.

In 2019, Florence County, SC had a population of 138k people with a median age of 39.2 and a median household income of $47,058. Between 2018 and 2019 the population of Florence County, SC declined from 138,561 to 138,475, a −0.0621% decrease and its median household income grew from $45,479 to $47,058, a 3.47% increase.

98.7% of the residents in Florence County, SC are U.S. citizens.

The largest universities in Florence County, SC are Florence-Darlington Technical College (769 degrees awarded in 2019), Francis Marion University (704 degrees), and Kenneth Shuler School of Cosmetology-Florence (84 degrees).

In 2019, the median property value in Florence County, SC was $131,900, and the homeownership rate was 65.7%. Most people in Florence County, SC drove alone to work, and the average commute time was 22.5 minutes. The average car ownership in Florence County, SC was 2 cars per household.

Florence County, SC borders Clarendon County, SC, Darlington County, SC, Dillon County, SC, Lee County, SC, Marion County, SC, Marlboro County, SC, Sumter County, SC, and Williamsburg County, SC.