Darlington, county, northeastern South Carolina, U.S. It lies for the most part on the rolling hills of the Coastal Plain, bounded to the northeast by the Great Pee Dee River and on parts of the southwestern border by the Lynches River.

In 2019, Darlington County, SC had a population of 67k people with a median age of 41.4 and a median household income of $38,448. Between 2018 and 2019 the population of Darlington County, SC declined from 67,253 to 67,027, a −0.336% decrease and its median household income grew from $36,254 to $38,448, a 6.05% increase.

99.3% of the residents in Darlington County, SC are U.S. citizens.

The largest universities in Darlington County, SC are Coker University (293 degrees awarded in 2019).

In 2019, the median property value in Darlington County, SC was $92,600, and the homeownership rate was 69.6%. Most people in Darlington County, SC drove alone to work, and the average commute time was 21.9 minutes. The average car ownership in Darlington County, SC was 2 cars per household.

Darlington County, SC borders Chesterfield County, SC, Florence County, SC, Kershaw County, SC, Lee County, SC, and Marlboro County, SC.